Authorities say 44-year-old Michele Kalina of Reading conceived the babies through an extramarital affair with a man unaware of her pregnancies.
They say the nurse's aide also bore a daughter with him who was given up for adoption in 2003.
A call to her public defender was not immediately returned on Monday.
Kalina and her husband have a teenage daughter and had a son who died in 2000 after a long illness.
Police say the daughter and husband found the remains in a closet, some in concrete and some in a plastic cooler.
Kalina has been in custody since August on abuse-of-corpse charges.