The crash happened around 9:00 p.m. on Woodhaven Road and Knights Road.
Investigators say the two vehicles collided in the eastbound lanes of Woodhaven..
All four people, which included a 35-year old man, a 24-year old woman and a 4-year old girl, were rushed to Aria Hospital - Torresdale Division. .
There was no word on the age of the fourth victim..
This crash remains under investigation..