Authorities now tell Action News that an elderly woman who lived in the home died in the blaze.
The fire started just after 7 a.m. Friday along the 3100 block of Fennel Road in Upper Hanover Township.
Firefighters say when they arrived on the scene the building was completely engulfed in flames and propane tanks were exploding.
Several fire companies from throughout Montgomery County sent help to battle the blaze. There were no hydrants near the remote home, so tanker trucks had to haul water to the scene.
They could not get inside until the flames were finally extinguished.
Once in they found the body of a 66-year-old woman. The Montgomery County Coroner's office said a family member will be needed to identify the body.
The SPCA also arrived on scene and took possession of several live ducks and chickens that were found caged outside the residence.
The cause of the blaze remains under investigation by both the Montgomery County fire marshal and the Pennsylvania State Police fire marshal.