The accident occurred shortly after 8:00 a.m. at the intersection of South Bridgeton Pike and Elk Road.
New Jersey Transit officials say their driver told them that the driver of the car slid along the roadway and into the intersection, resulting in the two vehicles contacting one another.
Both the driver and an occupant of the car were air lifted to Cooper University Trauma for treatment. There is no word on their condition.
The driver of the bus was not injured and there were no passengers on the bus.