Kardashian, 30, and Humphries, 26, tied the knot Saturday night in the exclusive Montecito area near Santa Barbara, Calif., Kardashian publicist Jill Fritzo told People magazine and E!
The ceremony will be televised as a two-part special on E! in October.
It is the first marriage for Humphries, who last played for the NBA's New Jersey Nets, and the second for Kardashian, star of E!'s "Keeping Up with the Kardashians." She was married to music producer Damon Thomas from 2000 to 2004.
People and E! reported Kardashian wore an ivory gown designed by Vera Wang. Her stepfather, Bruce Jenner, walked her down the aisle in front of 440 guests, including Demi Lovato, Mario Lopez, Eva Longoria, Sugar Ray Leonard, Alan Thicke and Lindsay Lohan.
Kardashian's gown had a tulle skirt, basque waist and Chantilly lace, and was matched with a pair of Giuseppe Zanotti shoes, the media outlets reported. The bride planned to wear two other Wang dresses before the night and the party were over.
Her sisters and TV co-stars Kourtney Kardashian, 32, and Khloe Kardashian, 27, served as co-maids of honor.
The groom wore a white peak lapel tuxedo jacket, black tuxedo pants and, a white shirt and a white bow tie, all designed by Ermenegildo Zegna.
Kardashian and Humphries began dating late last year and announced their engagement in May. He proposed on bended knee with a 20.5-carat ring by spelling out "Will you marry me?" in rose petals.
Since the couple's engagement, the pending nuptials have provided constant fodder for the media and the Kardashians, who posted updates about the wedding on their blogs and websites.
The waves of hype that preceded the ceremony didn't seem to faze the bride. Earlier this week, Kardashian said she was "totally calm" about the much-hyped ceremony.
"I think that freak-out moment kind of already passed," she said at a party Wednesday to launch her new clothing line at Sears.