The shooting happened at 11:59 p.m. Tuesday on the 800 block of South 22nd Street.
Police say 17-year-old girl was shot in the left leg. A 24-year-old man was shot in the buttocks. Both victims were transported to the hospital in stable condition.
Police say a group of juveniles fled the scene. Authorities are also looking for a blue BMW that fled the scene.
There is no word on a motive at this time.