Tuesday's edition of the hit ABC show marked the last dance for Bono. Despite his cheerful, spirited style, he had struggled from the beginning and came in last in the judges' assessment the night before.
The transgender activist said he came on the program "to show America a different kind of man."
Soccer star Hope Solo, who also was in jeopardy, avoided dismissal and will stay in contention. Six celebrities remain in the contest.
Judges' scores combined with viewer votes determine who is kicked off the show each week.