The popular weekday talk show is announcing that Seinfeld will join continuing co-host Kelly Ripa for three days, airing Nov. 21-23.
The show said Tuesday that guests scheduled to join Ripa and Seinfeld are actor Jason Segal, actress Kim Cattrall, comedian-host Howie Mandel, "Naked Chef" Jamie Oliver and that fabulous Muppet, Miss Piggy.
Philbin is departing the show Nov. 18 after 28 years as its host. There are no plans to immediately announce a permanent successor.
The soon-to-be-renamed "Live! with Kelly" will continue to air in most cities at 9 a.m. Eastern time.