The break in happened along the 7300 block of Medrick Place just before 11:00 p.m.
Police found two men shot inside the home, and a third victim shot on the sidewalk.
They believe a fourth possible victim showed up at the hospital a short time later.
Authorities believe this was a drug related home invasion and they found marijuana and scales inside the home.
All four victims are in critical but stable condition.
No arrests have been made.