The accident happened around 11:30 a.m. at the intersection of New Freedom Road and Eayrestown Road in Southampton Township.
Emergency crews responded to the scene and are currently working to free someone from the wreckage.
Authorities say just the two drivers were involved in the accident. The driver of the Volkswagen is said to have suffered serious injuries.
A medical helicopter has been called to the scene to transport the victim to the hospital.
