David Ojong, head of mission for Team Cameroon, said the seven all currently hold visas permitting them to remain legally in Britain until at least November.
Ojong said five boxers, a swimmer and a soccer player left the athletes' village at the Olympic Park in Stratford, east London, over the weekend and have not returned.
He named the missing athletes as swimmer Paul Ekane Edingue, women's goalkeeper Drusille Ngako and five boxers: Thomas Essomba, Christian Donfack Adjoufack, Abdon Mewoli, Blaise Yepmou Mendouo and Serge Abomo.
He said the Cameroon delegation consisted originally of 59 people, but 28 already have returned home, 24 remain in London and seven are missing.
Britain's Home Office, responsible for immigration, said it could not comment on whether any of the seven had applied for asylum.
Scotland Yard said it had received no report that any Cameroon athletes were missing.
Before the Olympic opening ceremony July 27, Sudan's embassy confirmed that three athletes had gone missing. The Sudan trio had attended a training camp, but missed the cut for the Olympics. Sudan's embassy said one had applied for asylum and the two others were expected to do so.