Emergency dispatchers said the blaze in Lancaster was reported shortly before 4:30 a.m. Monday.
The (Lancaster) Intelligencer/Lancaster New Era says Lancaster Fire Chief Tim Gregg told reporters that the 38-year-old woman and the girl were on the second floor and unable to escape the blaze.
Officials said a man and a teenage boy who were sleeping in the basement were able to reach safety.
Fire officials said one firefighter was flown to Crozer-Chester Medical Center with burn injuries and later listed in critical but stable condition. Two other firefighters were treated and released.
The cause of the fire remains under investigation.
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Information from: Intelligencer Journal/Lancaster New Era , http://lancasteronline.com
