The incident occurred just before 10:00 p.m. Saturday on the 400 block of Robinson Drive in the Dunlieth community.
Police responded to a report of gunfire and arrived to find several casings in the area and a vehicle that had been damaged as a result of the shooting.
A short time later, police were told that a man arrived at Wilmington hospital suffering from a gunshot wound and had been on Robinson Street with some friends.
According to police, the victim had been struck and taken in a private vehicle to the hospital.
So far, no arrests have been made and investigators are conducting interviews and trying to determine a motive.
Anyone with information is asked to contact the New Castle County Police Department.