The accident happened shortly after 10:00 a.m. Friday in the 7100 block of Millville-Mays Landing Road.
A construction pickup truck left the roadway, struck a tree and then caught fire.
The male driver of the truck was killed.
New Jersey State Police say a Trooper responding to the scene somehow suffered an ankle injury.
There is no word on the victim's identity at this time or on what may have caused the driver to lose control.