Fire officials say the blaze was reported shortly after 2 a.m. Thursday in Macon. The Telegraph of Macon reports that the first firefighters to arrive were able to rescue a man and two teenage boys.
Bibb County Coroner Leon Jones says fire crews found the bodies while fighting the flames.
Jones identified the victims as 36-year-old Jennifer Caffee; 13-year-old Elizabeth Caffee and 5-year-old Holly Tucker. Also killed was 10-year-old Wendy Chapman, who had cerebral palsy and used a wheelchair.
The 38-year-old man and two teenage boys were taken to a hospital.
Jones says investigators found no evidence of working smoke detectors in the house.