Shonda Rhimes, the show's creator and executive producer, said she's grateful for what she called the actress' "brilliant" work. Rhimes said "Grey's Anatomy" will savor Oh's character of Dr. Cristina Yang in the upcoming 10th season and then give her the exit she deserves.
Oh's publicist didn't respond Wednesday to requests for comment.
ABC said it intends to keep "Grey's Anatomy" on its schedule for years to come and with as many of the original cast as possible.
Others who have left the drama include Katherine Heigl and T.R. Knight.
Stars Ellen Pompeo as Dr. Meredith Grey and Patrick Dempsey as Dr. Derek "McDreamy" Shepherd have been with "Grey's Anatomy" since its 2005 debut.
