Authorities released surveillance video of the incident from Lee's Steaks and Hoagies at 5708 Germantown Avenue at 5:20 a.m. Tuesday.
Investigators say the suspects broke in through the roof and then stole cash and a bunch of cigarettes.
Suspect #1 is described as black male, 18 to 25 years-of-age, 5'7, thin build, facial hair, wearing a gray hooded sweatshirt, dark colored sneakers and white socks covering his hands.
Suspect #2 is described as a black male, 18 to 25 years-of-age, 5'7, thin build, facial hair with sideburns, wearing a gray hooded sweatshirt, white towel or shirt covering his face and gray sweatpants.
Anyone with information is asked to contact Philadelphia Police at 215-686-TIPS (8477), text a tip to PPD TIP (773847) or through PhillyPolice.com.