The Grammy-winning superstar was headed home alone when the accident occurred Friday night in Summerlin.
Police Lt. Ken Romane told the Las Vegas Review-Journal that it's uncertain whether a sobriety field test was conducted, but Santana was not driving under the influence.
Romane did not know the make of Santana's vehicle or the extent of damage to it and the parked car. Romane said the accident was "minor."
According to his concert schedule, the 66-year-old Santana performed on Thursday and Saturday nights but not on Friday night.
Santana has won 15 Grammys and is best known for the album "Supernatural," which has sold more than 25 million copies.