It was 1:32 a.m. when police responded to the 1700 block of West 2nd Street.
Police say the preliminary investigation suggests that the victim exited a residence in the 1700 block of West 2nd Street and fell into the roadway. Investigators say alcohol appears to be a contributing factor.
A westbound red pickup truck with a horizontal stripe running the length of the vehicle struck the victim as he was lying in the roadway. Witnesses say the vehicle continued westbound out of sight.
Officers performed CPR on the victim who was then transported to Christiana Hospital where he was pronounced dead.
The victim's name is withheld pending notification of next of kin.
Anyone with information is urged to contact police at 302-576-3691, Wilmington Police Confidential Tip Line at 302-576-3990, or Crime Stoppers at 1-800-TIP-3333.