The incident happened just before 2:00 a.m. Thursday at the intersection of 11th and Cumberland Streets.
Two police vehicles were parked in the area for a separate vehicle investigation.
Police say a 22nd District officer was sitting in one of the vehicles, a police SUV, when a red minivan came barreling the wrong way up Cumberland and hit a parked vehicle on 11th Street.
The minivan bounced off the parked car then hit the officer's SUV, setting off a chain-reaction crash that damaged the other unoccupied police vehicle and several other parked cars as well.
One car was hit so hard it was pushed off the street and up a 4-foot embankment.
One investigator told Action News it was fortunate the driver of the minivan struck a parked car first and not the police SUV.
The officer in that SUV was taken to the hospital.
He is being treated for back pain and is listed in stable condition.
The driver of the minivan was arrested for DUI and taken to the hospital in serious but stable condition.
Investigators say some narcotics were found in the minivan.
Police have closed off the area, which is littered with debris, as they investigate the crash.