Study: Breast cancer linked to bacteria

Researchers find different types and levels of bacteria in breast cancer and non-cancer patients

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Monday, October 23, 2017

CLEVELAND, Ohio (WPVI) -- Doctors think they've found a link between breast cancer and the bacteria in our bodies.

A team at the Cleveland Clinic found differences in the types and amounts of bacteria between cancerous and non-cancerous breast tissue.

For the study, researchers examined the tissues of 78 patients who underwent mastectomies related to breast cancer.

"And lo and behold, there was some bacteria that were over-represented in breast cancers compared to non-cancer breast tissues, and vice versa," says Dr. Charis Eng, a co-author of the study.

Previous research shows that when bacteria in the gut is imbalanced, it's easier for diseases - possibly including breast cancer - to grow.

If their theory is proven, it may explain why the majority of breast cancers have no genetic ties.

Dr. Eng says the next step is to look at whether they could target the bacteria that is specifically in the breast cancer tissue with treatment, or even better, pinpoint the problem area and target it before the breast cancer has a chance to develop.

She hopes that discoveries made in this research will someday lead to better and less harsh treatments for breast cancer, for instance, treating people with a targeted probiotic instead of chemotherapy.

"Imagine if we could, instead of giving chemotherapy, that not only hits the cancer, but every cell in the body, imagine if we could just give something that targets the cancer, wherever it may be, breast or otherwise," says Dr. Eng.

Complete results of the study can be found in the journal OncoTarget.

Breast cancer is the second most common cancer among women in the U.S., affecting one in every eight women.