It happened at 4 a.m. inside the Wayne Food Market on the 4300 block of Wayne Avenue.
Police say the two unknown suspects broke into the market by cutting a hole in the ceiling.
Once inside, surveillance cameras caught the duo rummaging through the store.
Click here to watch the surveillance video
They got away with several cartons of cigarettes and an unknown amount of cash before fleeing the store back through the ceiling, police said.
If you see these suspects do not approach them, and contact 911 immediately.
Anyone with information is asked to call police at 215.686.TIPS (8477) or text a tip to PPD TIP or 773847.
You can also submit an anonymous tip online at PhillyPolice.com.