The incident happened just before 3:30 p.m. on the 1400 block of W. Norris Street.
Police say a Yamaha dirt bike was traveling southbound on Broad Street approaching Norris Street on the sidewalk.
A silver Jeep was northbound on Broad Street, making a left turn onto Norris Street when it made contact with the dirt bike rider.
The driver of the Jeep remained on the scene.
The 30-year-old man on the dirt bike was taken to Temple University Hospital, where he was later pronounced dead.
There is no word of any arrests made at this time.