It happened around 10 p.m. Wednesday in the 4900 block of Whitaker Avenue.
According to Chief Inspector Scott Small, a 30-year-old man driving a Nissan SUV was killed after being struck by the driver of an Acura.
A 30-year-old woman, who was 5-months pregnant, was also inside the SUV. She was rushed to the hospital.
The woman remains in critical condition, but police confirmed to Action News on Sunday that her child did not survive.
Police say 42-year-old Charles Smith was driving the Acura with a female passenger when they allegedly hit the SUV, which then slammed into a utility pole and two parked vehicles.
Police say both Smith and his passenger appeared to be impaired at the scene. Both were not injured in the crash.
Authorities tell Action News that Smith is being charged with murder, homicide by vehicle while DUI, among other related charges.