Several people were trapped under the tree at Whittier's Penn Park, the Los Angeles County Fire Department said.
Video from the scene showed fire crews using chain saws to cut through the downed branches.
Four of the injured suffered scrapes and bruises and one had moderate injuries, officials said.
Witnesses described hearing a loud crack and seeing people run from the area.
2 trees fell during a wedding at Penn Park, multiple people injured... pic.twitter.com/zuVf9h60TN— pat (@ChiefPat_) December 18, 2016
The tree could have been weakened by California's ongoing drought and recent heavy rain could have contributed to its fall, officials said.
An arborist will assess the area on Sunday, officials said.