It happened around 9:30 p.m. Thursday on the 5000 block of North Camac Street.
The victims were found by police officers patrolling the area of Camac Street and Lindley Street.
They were taken to Einstein Medical Center for treatment, both with a gunshot wound in the left side of their chests.
The first victim, a 26-year-old male, was admitted in stable condition. The other victim, a 30-year-old male was admitted in critical condition.
Police say a man was seen on surveillance walking a pitbull in the area where the shooting occurred and he is considered a person of interest.
Police are asking anyone with information on this shooting to give them a call at 215.686.TIPS (8477) or text a tip to PPD TIP (773847).
Click here to watch the surveillance video