It happened at R+L Supermarket on the 4200 block of Germantown Avenue.
Police say the burglar broke into the supermarket around 3:30 a.m. by climbing a ladder from a second floor room.
The thief was then caught on surveillance video climbing through the supermarket ceiling.
Click here to watch the surveillance video
Once inside the suspect used a long screwdriver to pry open the cash register drawer.
He stole an unknown amount of cash before fleeing the scene.
Police describe the suspect as a black male with a medium build. He was wearing a red sweatshirt, white scarf covering his head, jeans and sneakers.
Anyone with information on this burglary should call police at 215.686.TIPS (8477) or text a tip to PPD TIP (773847).