The incident happened back on June 28 on the 1700 block of South Christopher Columbus Boulevard.
The unknown male suspect was caught on surveillance video leaving the nightclub at 3:00 a.m.
Click here to watch the surveillance video
Police say the man started arguing with a group standing outside waiting for a taxi when he suddenly punched one man in the head.
The suspect then punched another man, knocking him unconscious before fleeing in a taxi.
Police describe the suspect as a white male in mis mid to late 20s, over 6'0" tall with short brown hair and a muscular build. He was wearing a black polo shirt and khaki pants.
If you see this suspect do not approach him, contact 911 immediately.
Anyone with information on this crime should call police at 215.686.TIPS (8477) or text a tip to PPD TIP (773847).
You can also submit an anonymous tip online at PhillyPolice.com.