17-year-old Dashon Glover was hit three times by gunfire. He died a short time later at an area hospital.
The shooting left another teen critically wounded, with a gunshot wound to the thigh.
It was just after 10:30 p.m. Sunday when multiple 911 calls brought officers to the 500 block of North Creighton Street at Wyalusing Avenue.
There they found Glover, who had been in the head, arm and leg.
Homicide investigators say an argument preceded the shooting.
"We are hearing those two males got into an argument with an unidentified male and female. The male pulled out a gun and started shooting at the two 17-year-olds," said Capt. James Clark of the Homicide Unit.
Neighbor Ben Gerald told Action News he heard "like 5 gunshots - bang, bang, bang, bang, bang, you know? I wasn't about to stick my head out there."
Around the corner from the shooting scene, in the 500 block of Paxon Street, the teen wounded in the thigh managed to sprint door-to-door, seeking shelter as he lost a massive amount of blood.
A stranger took him in, and medics rushed him to the hospital.
Other residents who didn't hear him woke up to find blood on their porches. Blood still stained the roads at Creighton and Wyalusing later in the day.
"Blood on my steps, my porch, my doorknob. It seems like he must have knocked on my door, one of the victims knocked on my door, tried to get in or something," said one neighbor, too fearful to show his face or give us his name.
Police interviewed multiple witnesses overnight, including the person who let the wounded teen in their home.
They have released the following descriptions of the two suspects:
#1: Light-skinned black male, mid-20s
#2: Dark-skinned black female, 5'10", wearing a black leather coat and blue-and-white leggings, carrying a yellow and black book bag.
Anyone with information is asked to contact Philadelphia Police.