It happened just before 7 p.m. on the 2100 block of 72nd Avenue in West Oak Lane.
According to investigators, a 30-year-old man was violently gunned down by a suspect who entered the convenience store.
"Clearly this 30-year-old victim was the intended target," said Philadelphia Police Chief Inspector Scott Small.
Authorities said security cameras inside and outside of the business provided investigators with a good look at the gunman. Police said he appeared to be wearing a Nike hooded sweatshirt, track pants and Nike sneakers.
At least 14 shots were fired inside the store.
Police said there were at least 10 other people inside at the time, six employees and the rest were customers.
"Most of the spent shell casings are just feet (away) and some are just inches away from where this victim is lying," Small said. "The shooter walked right up to this individual and fired multiple shots."
Police said most disturbing of all was what occurred after the gunman initially opened fire.
"You see the shooter run towards the front door of the property, then turn around and he runs back to the victim who is lying on the floor of the store. And when the shooter runs back, he stands over the victim and fires a second string of shots from point-blank range," Small said.
No weapon has been recovered. Police are hopeful the security cameras will quickly lead to an arrest.
Anyone with information is asked to call police 215-686-TIPS.