It happened around 12:25 a.m. on the 1400 block of South Vogdes Street.
Police said both were shot outside of their house by a person known to the family.
They were both taken to Penn Presbyterian Hospital in critical condition. Police said the 42-year-old man subsequently died there.
According to investigators, an argument preceded the shooting.
Police continue to investigate the incident.
**This story is developing. Check back with 6abc.com for updates.***