Wilkins, the 55-year-old former Atlanta Hawks star, hit a half-court shot after 57.6 seconds in the final round to seal Team Bosh's three-peat.
They topped Russell Westbrook, Anfernee Hardaway and Tamika Catchings in the final round, when Team Westbrook ran out of time after 90 seconds.
Houston's Patrick Beverley came from behind to beat Brandon Knight of the Milwaukee Bucks in the final round of the skills competition. The Rockets' defensive specialist, who replaced Washington's John Wall in the dribbling, passing and shooting competition, made a 3-pointer to clinch the win.
Unlike in the past, two players competed against each other in a bracket-style format for the skills challenge. Beverley bested Atlanta's Jeff Teague in the semifinals. Knight overtook Toronto's Kyle Lowry in the other semifinal.
In the shooting stars contest, Stephen Curry and his father, former NBA player Dell Curry, and WNBA star Sue Bird were knocked out in the opening round along with Paul Millsap, Scottie Pippen and Elena Delle Donne.
Curry found redemption in later winning the 3-point contest.
Giannis Antetokounmpo, Victor Oladipo, Mason Plumlee and Zach LaVine were competing in the slam-dunk contest.
In a twist, this was a rare year when the 3-point competition has more intrigue than the dunk contest because of the notable names who are -- and aren't -- participating in each.
Curry and fellow "Splash Brothers" star Klay Thompson of the Golden State Warriorsadvanced to the championship round, with Curry posting a 27 to Thompson's 14. Cleveland'sKyrie Irvinghad a final-round 17.
Information from The Associated Press was used in this report.
Team Bosh Wins Shooting Stars For Third Time
The team of Chris Bosh, Dominique Wilkins and Swin Cash defeated Team Westbrook in the Degree Shooting Stars competition.