It happened before 9:30 a.m. Wednesday.
Video from Chopper 6 HD showed more than a dozen firefighters surrounding a blue vehicle with extensive damage to the hood and windshield.
The firefighters appeared to be working to free someone from the wreckage.
There was no immediate word on the number or extent of injuries.
One lane of traffic was getting by on the shoulder. Traffic was backed up for several miles approaching the scene.
The crash was cleared after 10 a.m., but delays remained.
Motorists were advised to seek alternate routes.