Photos shared by CHOP show the babies all dressed up in costumes as they took part in a special photoshoot to celebrate the holiday.
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The costumes ranged from a chili pepper, to a football player and everything in between.
CHOP NICU babies dress up for Halloween in adorable photoshoot
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Some of the families also got in on the fun and posed for photos with the babies.
The hospital says opportunities like this are just a feel-good way for families to feel happy and enjoy the fall season, despite being in the hospital.