And taking the stage as part of this production is a hometown star.
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West Oak Lane's Ta'Rea Campbell plays Angelica Schuyler. She's overwhelmed with emotion ahead of the show's debut.
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"This pandemic really put everybody through a lot of things," she said. "I just continually feel blessed to be able to tell this story and this is like icing on the cake. It's wonderful to be able to tour with 'Hamilton,' but it's always wonderful to be able to tour on your home turf."
And this opportunity is all very full circle for Ta'Rea. The first time she took the stage at the Academy of Music was at her high school graduation.
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"I graduated from CAPA and we didn't have a stage big enough at the time, so that's where our graduation was held," she said.
Ta'Rea came back to that iconic stage for a touring production of "Sister Act," and now, she returns to her home town with a starring role in "Hamilton."
"Hamilton" opens on October 20th and runs through November 28th at the Academy of Music.
Tickets are now available at KimmelCulturalCampus.org, in person at the Academy of Music box office (240 South Broad Street) or by calling 215-893-1999.