It happened around 11 p.m. at the store at North Broad and Champlost streets, which is located across from the 35th police district headquarters.
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Authorities say the driver was speeding on Broad Street with police in pursuit before the vehicle careened into the T-Mobile store sending glass and metal everywhere.
Workers in a nearby business felt the impact, as did nearby residents.
"It sounded like a train had hit a car. It shook my house," said neighbor Nick Kelly.
Driver crashes into T-Mobile store during police chase
The suspect was able to get out of the car and fled on foot.
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A foot pursuit ensued and police were able to take him into custody.
No serious injuries were reported.
Police say a gun was recovered.
Overnight, the car was hauled out of the T-Mobile storefront at the Shops at Champlost.
On Wednesday morning, crews were shoveling shards of glass, sweeping, and clearing debris.
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"Calm down Philly, calm down," remarked one passerby as she surveyed the damage.
What prompted the chase remains under investigation.
RELATED: Check the 6abc Neighborhood Safety Tracker