The crash involved a SEPTA bus, officials say.
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Police said it happened on 16th and Walnut streets just before 9 p.m. when a SEPTA bus crashed into a building.
READ | Action News talks to SEPTA management after 3 collisions around Philadelphia area
Action News talks to SEPTA management after 3 collisions around Philadelphia
Officials said the driver sustained minor injuries, and no other passengers were onboard at the time of the wreck.
The building only sustained minor damage from the crash, with the bus piercing the front window.
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As of 11 p.m., crews were on the scene removing the bus from the building. Power may be impacted while crews clean up the area.
This incident is the fourth crash involving a SEPTA vehicle within a week.
In the first crash, two SEPTA buses collided resulting in 19 injuries on Roosevelt Boulevard in Philadelphia.
A 72-year-old passenger, Siu Nam Mak, was killed as a result.
The next incident involved a SEPTA bus that struck an electric box in the city's Fishtown neighborhood, injuring four passengers.
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Another incident involved two SEPTA trolleys, which struck one another and caused minor injuries in Delaware County.
This crash also comes on the heels of an Action News interview with SEPTA's new Chief Safety Officer Ronald Keele.
Keele told Investigative Reporter Chad Pradelli that due to these recent wrecks, extra safety training was being implemented.
"Like I said, we take it seriously here. So the one thing just because you know, it doesn't happen every day, we still look at safety every day," Keele told Pradelli. "We try to prevent these from happening. But like everything else, things do occur."