It happened around 9:30 p.m. Tuesday on the 2700 block of S. Front Street.
Police say a 28-year-old man was shot in the chest. He was transported to an area hospital where he was later pronounced dead. The victim has not been identified.
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Chopper 6 was overhead as officers cordoned off a large area of the parking lot.
Man injured after shooting in parking lot of Philadelphia gentlemen's club
Police say the incident started as two men with guns approached the victim and another man, insisting on going through their pockets.
The 28-year-old was shot during a struggle.
The robbers drove off with a cellphone.
No arrests have been made.
Anyone with any information is asked to call police at 215-686-TIPS.