It happened just before 6 a.m. Sunday on the 2400 block of N. 29th Street in the city's Strawberry Mansion neighborhood.
At the scene, officers found a 43-year-old woman who had been shot in the face inside the store.
SEE ALSO: Woman shot, killed while shopping at Philadelphia corner store; suspect sought by police
Woman shot, killed while shopping at Philadelphia corner store; suspect sought by police
She was pronounced dead at the scene. Officials have not released her identity at this time.
On Thursday, police released an image of a suspect wanted for questioning by the Philadelphia Police Homicide Division.
The suspect may be driving a tan in color Infinity SUV Qx4 with heavy front-end damage on the passenger side of the vehicle.
Anyone with information is asked to call police at 215-686-TIPS.