The two infected individuals are unvaccinated men in Kent County.
RELATED: Unvaccinated Kent County man becomes 1st Delaware measles case in more than a decade
Healthy officials continue to identify and notify those who may have been exposed to the virus.
Delaware's Department of Health and Social Services says more than 60 people were vaccinated at clinics and mobile health units just on Tuesday.
The MMR vaccine has been shown in tests to be 97% effective in preventing measles.