The incident happened just after 10 a.m. on the 200 block of W. Oxford Street.
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Police say a 48-year-old man attacked his 67-year-old father. The father then shot the son one time in the groin.
According to authorities, a struggle ensued in which the son got control of the weapon. The son then shot the father one time in the head.
Both are conscious and are being transported to Jefferson University Hospital by medics.
They are currently being listed in critical condition.
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A weapon has been recovered by police.
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