A Route 38 bus collided with the passenger side of a Jeep Cherokee at Broad Street and JFK Boulevard in Center City, officials say.
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There was a person sitting on the side of the vehicle that was struck.
Investigators say the driver of the Jeep stepped outside the vehicle to speak with police after the crash.
SEPTA bus and trolley operators are currently undergoing safety training due to a recent string of crashes.
There have been at least eight reported crashes involving SEPTA vehicles this summer.