Eagles running back Darren Sproles originally hurt his hamstring in practice leading into Week 2 and injured it again in Wednesday's practice, according to sources.
The Bucs are expecting RB Doug Martin, who hasn't played since Week 2 because of a hamstring injury, to play against the Bears on Sunday.
Bills coach Rex Ryan said LeSean McCoy's status vs. the Dolphins remains unclear after the running back practiced on a limited basis Friday.
Bills running back LeSean McCoy will miss Sunday's game after injuring his hamstring in Wednesday's practice, a source told ESPN.
Bucs RB Doug Martin, who was second in the NFL in rushing last year, will likely miss three weeks with an injured hamstring, a source told ESPN.
Rob Gronkowski is out for a second straight week as the Patriots tight end tries to overcome a hamstring injury suffered in August.