The crime happened around 11 p.m. on Thursday, April 18 in the 7700 block of Lindbergh Boulevard.
The video starts out showing three women inside the victim's apartment, gathered around a table eating.
Police believe they're all in their early twenties.
"At some point while the females are there, there's a knock at the door. One of the females opens the door and she's accompanied by the victim who resides in that apartment," said Capt. Sekou Kinebrew of the Philadelphia Police Department.
As the victim comes to the door with one of the women, two men dressed in black hoodies enter the apartment and fire shots.
The victim, 33-year-old Nana Opoku, was shot in the chest and died at the scene.
"The video is rather graphic. It's clear enough where if you know these individuals or encountered them in the past you would recognize them," said Kinebrew.
Outside the apartment, another camera shows a gray Chevrolet Malibu pulling into the parking lot before the shooting.
After the shooting, police say you can see the two male suspects and the three females all run to that car and leave.
"The video will go on to show... the females enter the vehicle of the people that committed the shooting. For that reason we are classifying them as suspects as well," said Kinebrew.
There has been no word on a motive. Detectives do not believe anything was taken from the apartment.
Tips can be made anonymously at (215) 686-TIPS.
As with all unsolved homicides in Philadelphia, there is a $20,000 reward being offered for information that leads to an arrest and conviction.