It happened at Paddy's Old City Pub located at 228 Race Street.
Surveillance video shows the burglars forcing open the front door with a crowbar around 3:30 a.m.
After an hour inside the bar, they can be seen stealing two flat screen TVs.
The pair then carried the entire ATM machine out through the front door.
Police describe the first suspect as a black male, 40-50 years-old, 6'0 tall with a medium to stocky build and mustache. He was wearing glasses, light colored hat, light colored jacket with a black hooded sweatshirt underneath, light colored pants and light colored Nike sneakers.
The second suspect is described as a black male, 40 years-old 5'7"-5'9" tall with a thin build. He was wearing a dark baseball style cap, dark jacket and jeans with a design on both rear pockets, possibly a skull.
Anyone with information should call police at 215.686.TIPS (8477) or text a tip to PPD TIP (773847).
VIDEO: Click here to watch the surveillance video