With 7 minutes, 1 second left in the fourth quarter, Anthony confronted a fan standing behind the row of courtside seats near center court at the Wells Fargo Center. Anthony said afterward that the fan referred to him as "boy."
Play was paused for several minutes while security personnel advanced to the spot of the confrontation and refs guided Anthony away from the incident.
"Some things were said," Anthony said afterward. "Unacceptable. I'm cool with fans heckling, fans talking trash, cheering for their team, booing the other team, I'm all for that. But when you cross certain lines, as a man, you just, that's what you're going to see. That's what you're going to get, as you saw there."
While things were being sorted out, another fan seated courtside taunted Anthony using similarly offensive language, according to Anthony.
Sixers center Joel Embiid came to Anthony's side when the courtside fan attempted to escalate things.
"I was just trying to calm the situation because they were just going back and forth, and I really wanted to just go home and finish the game," Embiid said. "So, yes, that's what I wanted, to calm the situation down so we could play and move on."
A Sixers spokesman told ESPN that one fan was ejected and that the Wells Fargo Center would be in charge of any further discipline. An email to Wells Fargo Center security from ESPN was not immediately returned.
Anthony said he would accept any further steps that are taken to resolve the incident, but added that it would be "out of his hands."
"Unacceptable language and unacceptable behavior by fans is the simplest way to put it," Lakers coach Frank Vogel said. "There's got to be a higher standard. And hopefully that's handled the right way."
Lakers guard Russell Westbrook, who has had several in-game run-ins caused by inappropriate fan behavior over the years -- including in Philadelphia in 2016 and 2021 -- said that the fans Thursday night might have "crossed the line."
While Philadelphia sports fans certainly have a reputation, Anthony said that Thursday's incident didn't line up with his past experiences with the city as a visiting player.
"You play through the heckles. But that's all fun and games," he said. "I mean, I've been doing that for 19, 20 years. Especially playing here, it's been a great place to come in and play. And fans, I know how the fans are here.
"But there's just certain things you don't bring to any type of sporting event. There's just certain things you don't say to anybody. If I was outside and I bumped into you and you said those things to me, then it would be a totally different story."
Fan ejected after altercation with Melo
Carmelo Anthony has some words with a couple of 76ers fans in the crowd, leading to the ejection of one of them by security.