It happened around 5 a.m. Friday on a train near the 46th Street Station at 46th and Market streets.
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SEPTA officials say preliminary information indicates the victim was stabbed in the hand during an altercation on the train.
The victim was taken to the hospital for treatment.
SEPTA says a suspect was identified and taken into custody.
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Westbound service on the Market-Frankford Line was operating with delays due to police activity.
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