It happened around 11:52 p.m. on the 3100 block of US-206 in Mansfield Township.
Authorities said the driver lost control of the vehicle, struck a guard rail and flipped down an embankment before landing in the creek.
The Action Cam was on the scene as a crane pulled the damage car out of the water.
The driver and a passenger became trapped and were rescued from the car.
Both were taken to the hospital. There is no word on the extent of their injuries.