It happened around 4:30 p.m. on the 5800 block of North 15th Street, 20 blocks north of where six police officers where shot on Wednesday.
Chopper 6 captured police pulling one victim from a residence, placing him into a police car and rushing him to the hospital.
Police confirmed the five shooting victims were males ranging in ages from 17 to their mid-20s. All five were taken to the hospital.
One victim, shot in the head and chest, is listed in critical condition; the four others suffered non-life threatening injuries.
The street was riddled with around 26 shell casings leading police to conclude this wasn't a single shooter.
Investigators think the victims were targeted as they sat outside.
"Picking up a gun is not a way to handle your issues. Sadly, we got a small percentage of our young men who think that's the only way to deal with situations. So we got to break that culture, too ," said Police Commissioner Richard Ross.
No arrests have been made.
Anyone with any information is asked to call police at 215-686-TIPS.