The crash happened around 1:00 a.m. Friday at the intersection of E Chelten Avenue and Baynton Street.
According to investigators, the police cruiser was rear-ended by another car.
The officers suffered various injuries to the neck, head and pelvis. Both were transported to Albert Einstein University Hospital in stable condition.
The driver of the striking vehicle was taken into custody and is expected to face formal charges.
The identities of the officers and the suspect have not been released.